Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL28132433 | 0.98 | PLA2G10 (0.37) | PLA2G10HDAC10HDAC6VCPTP53 | |
| SCHEMBL8898917 | 0.78 | KMT2A (0.48) | KMT2AKIF11MAPTDAOKDM4E | |
| SCHEMBL28202823 | 0.75 | ALDH1A1 (0.50) | PLA2G10VCPTP53KMT2AKDM4E | |
| SCHEMBL28369134 | 0.73 | BIRC5 (0.44) | PLA2G10VCPMAPTKDM4EALDH1A1 | |
| SCHEMBL18503031 | 0.73 | NPY5R (0.37) | TP53KMT2AKIF11MAPTHSD17B10 | |
| SCHEMBL28246770 | 0.72 | ALDH1A1 (0.35) | PLA2G10VCPTP53KMT2AMAPT | |
| SCHEMBL28369168 | 0.72 | MAPT (0.46) | PLA2G10VCPTP53KMT2AMAPT | |
| SCHEMBL3672379 | 0.72 | DAO (0.42) | PLA2G10HSD17B10DAOHTR2AHTR2B | |
| SCHEMBL28251366 | 0.71 | KMT2A (0.36) | KMT2AMAPTDAOHTR2AKDM4E | |
| SCHEMBL28365059 | 0.71 | MDM2 (0.40) | PLA2G10VCPTP53MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106536481-B | The composition of Parasiticidal comprising indole derivatives, its usage and purposes | 勃林格殷格翰动物保健美国公司 | 2019-11-22 | — | — | CN | disclosed |