Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 4/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28369134 | 0.84 | BIRC5 (0.44) | MDM2MAPTPLA2G10VCPCYP19A1 | |
| SCHEMBL28202823 | 0.80 | ALDH1A1 (0.50) | PLA2G10TP53VCPCYP19A1ALDH1A1 | |
| SCHEMBL28365057 | 0.80 | CYP19A1 (0.46) | MDM2MAPTPLA2G10VCPCYP19A1 | |
| SCHEMBL28369113 | 0.80 | CYP19A1 (0.52) | PLA2G10VCPCYP19A1ALDH1A1TSHR | |
| SCHEMBL28365207 | 0.78 | KDM4E (0.47) | MDM2MAPTPLA2G10VCPCYP19A1 | |
| SCHEMBL28365347 | 0.75 | NOTUM (0.40) | MAPTPLA2G10TP53VCPCYP19A1 | |
| SCHEMBL28368802 | 0.75 | CYP19A1 (0.48) | MAPTRXFP1CYP19A1ALDH1A1TSHR | |
| SCHEMBL28369162 | 0.75 | CYP19A1 (0.43) | PLA2G10VCPCYP19A1ALDH1A1TSHR | |
| SCHEMBL28369168 | 0.71 | MAPT (0.46) | MDM2MAPTPLA2G10TP53VCP | |
| SCHEMBL28338755 | 0.71 | PLA2G10 (0.38) | MAPTPLA2G10TP53VCPCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107619385-B | Method for synthesizing 2-trifluoromethyl indole by palladium-catalyzed aryl enamine intramolecular amine | 温州大学 | 2020-02-21 | — | — | CN | disclosed |