Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | VEGFA | P15692 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20488360 | 0.81 | KDM4E (0.37) | PIK3C3RXRARXRBRXRGROCK2 | |
| SCHEMBL20487311 | 0.79 | TSHR (0.42) | PIK3C3RXRARXRBRXRGROCK2 | |
| SCHEMBL28340821 | 0.78 | PRMT5 (0.37) | HPGDVEGFAFLT1EGLN1EGLN3 | |
| SCHEMBL28340780 | 0.77 | PRMT5 (0.36) | HPGDVEGFAFLT1EGLN1EGLN3 | |
| SCHEMBL28338909 | 0.76 | ACHE (0.39) | PIK3C3RXRARXRBRXRGROCK2 | |
| SCHEMBL30125089 | 0.74 | MEN1 (0.33) | RXRARXRBRXRGHPGDEGLN1 | |
| SCHEMBL28937782 | 0.74 | MEN1 (0.33) | RXRARXRBRXRGHPGDEGLN1 | |
| SCHEMBL18555436 | 0.72 | TRPA1 (0.50) | PIK3C3RXRARXRBRXRGROCK2 | |
| SCHEMBL20488997 | 0.70 | TRPA1 (0.39) | RXRARXRBRXRGCYP1A2 | |
| SCHEMBL27395600 | 0.68 | SMN1; SMN2 (0.39) | ROCK2HPGDFLT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110603252-A | Aryl, heteroaryl and heterocyclic pharmaceutical compounds for the treatment of medical disorders | 艾其林医药公司 | 2019-12-20 | — | — | CN | disclosed |