Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.34 |
| ▸ | WNT1 | P04628 | 3/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | VEGFA | P15692 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28340821 | 0.85 | PRMT5 (0.37) | PRMT5WDR77SMN1; SMN2DYRK1AEGLN1 | |
| SCHEMBL20489045 | 0.83 | PRMT5 (0.37) | PRMT5WDR77DYRK1AWNT1KDM4E | |
| SCHEMBL26779901 | 0.81 | PRMT5 (0.38) | PRMT5WDR77DYRK1AWNT1CFD | |
| SCHEMBL28340781 | 0.78 | ACHE (0.36) | PRMT5WDR77DYRK1AWNT1KDM4E | |
| SCHEMBL28338908 | 0.77 | PIK3C3 (0.37) | PRMT5WDR77SMN1; SMN2EGLN1VEGFA | |
| SCHEMBL20488921 | 0.71 | PRKAG1 (0.39) | PRMT5WDR77DYRK1AWNT1 | |
| SCHEMBL20487955 | 0.70 | PRMT5 (0.37) | PRMT5WDR77KDM4EALDH1A1MAPT | |
| SCHEMBL18555982 | 0.70 | DYRK1A (0.56) | PRMT5WDR77DYRK1AWNT1 | |
| SCHEMBL20487651 | 0.65 | AXL (0.39) | PRMT5WDR77MAPT | |
| SCHEMBL24709225 | 0.65 | GSK3A (0.43) | DYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110603252-A | Aryl, heteroaryl and heterocyclic pharmaceutical compounds for the treatment of medical disorders | 艾其林医药公司 | 2019-12-20 | — | — | CN | disclosed |