Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597723 | 0.87 | ATM (0.50) | RAB9ASIGMAR1ATMCYP19A1CHRM1 | |
| SCHEMBL5494161 | 0.87 | ATM (0.50) | RAB9ASIGMAR1ATMCYP19A1CHRM1 | |
| SCHEMBL8547165 | 0.87 | ATM (0.50) | RAB9ASIGMAR1ATMCYP19A1CHRM1 | |
| SCHEMBL7233850 | 0.87 | ATM (0.50) | RAB9ASIGMAR1ATMCYP19A1CHRM1 | |
| SCHEMBL9328664 | 0.87 | ATM (0.50) | RAB9ASIGMAR1ATMCYP19A1CHRM1 | |
| SCHEMBL9200006 | 0.85 | CYP19A1 (0.45) | SIGMAR1CYP19A1ALDH1A1 | |
| SCHEMBL28339084 | 0.81 | RAB9A (0.44) | RAB9AATMALDH1A1GAA | |
| SCHEMBL5702004 | 0.81 | RAB9A (0.48) | RAB9ASIGMAR1CYP19A1CHRM1ALDH1A1 | |
| SCHEMBL5702051 | 0.81 | RAB9A (0.48) | RAB9ASIGMAR1CYP19A1CHRM1ALDH1A1 | |
| SCHEMBL7877679 | 0.81 | RAB9A (0.48) | RAB9ASIGMAR1CYP19A1CHRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110577490-B | Synthetic method of abamectin intermediate (2S,5S) -N-protecting group-5-hydroxy-2-piperidine formate | 山东安信制药有限公司 | 2020-09-22 | — | — | CN | disclosed |
| CN-110577490-A | synthetic method of abamectin intermediate (2S,5S) -N-protecting group-5-hydroxy-2-piperidine formate | 齐鲁天和惠世制药有限公司 | 2019-12-17 | — | — | CN | disclosed |