Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | CNR2 | P34972 | 2/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28215959 | 0.87 | L3MBTL1 (0.66) | L3MBTL1ADORA1CA12CA1CA2 | |
| SCHEMBL16344098 | 0.84 | KAT2B (0.49) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL1606606 | 0.83 | LMNA (0.80) | L3MBTL1ADORA1CA12CA1CA2 | |
| SCHEMBL5852445 | 0.83 | NPSR1 (0.81) | L3MBTL1ADORA1CA12CA1CA2 | |
| SCHEMBL25245909 | 0.82 | NR4A2 (0.67) | L3MBTL1KMT2ALMNAALDH1A1CNR2 | |
| SCHEMBL3865315 | 0.82 | L3MBTL1 (0.71) | L3MBTL1ADORA1CA12CA1CA2 | |
| SCHEMBL8418110 | 0.81 | CA12 (0.69) | L3MBTL1ADORA1CA12CA1CA2 | |
| SCHEMBL5625905 | 0.81 | ADORA1 (0.78) | L3MBTL1ADORA1CA12CA1CA2 | |
| SCHEMBL30049353 | 0.81 | POLB (0.79) | L3MBTL1ADORA1CA12CA1CA2 | |
| SCHEMBL17324721 | 0.81 | POLB (0.79) | L3MBTL1ADORA1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627705-B | N-benzyl indole thiosemicarbazone derivative, preparation and application | 西北农林科技大学 | 2021-07-16 | — | — | CN | claimed |
| CN-110627705-A | N-benzyl indole thiosemicarbazone derivative, preparation and application | 西北农林科技大学 | 2019-12-31 | — | — | CN | claimed |
| CN-110627705-B | N-benzyl indole thiosemicarbazone derivative, preparation and application | 西北农林科技大学 | 2021-07-16 | — | — | CN | disclosed |
| CN-110627705-A | N-benzyl indole thiosemicarbazone derivative, preparation and application | 西北农林科技大学 | 2019-12-31 | — | — | CN | disclosed |