Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880373 | 0.80 | KMT2A (0.51) | KMT2AALOX15MAPK1CYP3A4TSHR | |
| SCHEMBL146549 | 0.78 | KMT2A (0.38) | KMT2ACYP3A4TSHRL3MBTL1KDM4E | |
| SCHEMBL647119 | 0.76 | ELANE (0.39) | KMT2ACYP3A4KDM4EELANEALDH1A1 | |
| SCHEMBL30602529 | 0.76 | L3MBTL1 (0.56) | KMT2AALOX15L3MBTL1GLAKDM4E | |
| SCHEMBL2344510 | 0.76 | L3MBTL1 (0.56) | KMT2AALOX15L3MBTL1GLAKDM4E | |
| Ethylene SCHEMBL2040209 | 0.75 | KMT2A (0.47) | KMT2AALOX15MAPK1TSHRL3MBTL1 | |
| SCHEMBL10385058 | 0.74 | KDM4E (0.44) | MAPK1CYP3A4TSHRL3MBTL1GLA | |
| SCHEMBL2318328 | 0.74 | CREBBP (0.41) | KMT2AALOX15MAPK1CYP3A4TSHR | |
| Propane SCHEMBL27680106 | 0.74 | L3MBTL1 (0.54) | KMT2AALOX15MAPK1L3MBTL1GLA | |
| SCHEMBL27830742 | 0.74 | KMT2A (0.41) | KMT2AELANEALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621671-A | Benzofuran and benzothiophene derivatives as PGE2 receptor modulators | 爱杜西亚药品有限公司 | 2019-12-27 | — | — | CN | disclosed |