Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27673491 | 0.81 | LMNA (0.42) | SMN1; SMN2HPGDGSK3BALDH1A1NPC1 | |
| SCHEMBL27830742 | 0.81 | KMT2A (0.41) | ELANEKMT2AATMALDH1A1GAA | |
| SCHEMBL9351950 | 0.79 | GSK3B (0.41) | SMN1; SMN2KMT2AHPGDGSK3BNPC1 | |
| SCHEMBL28339384 | 0.76 | KMT2A (0.48) | ELANEKMT2AHPGDALDH1A1GAA | |
| SCHEMBL3137968 | 0.75 | ELANE (0.36) | ELANEKMT2AATMALDH1A1 | |
| SCHEMBL10804734 | 0.74 | HPGD (0.41) | SMN1; SMN2KMT2AHPGDGSK3BALDH1A1 | |
| SCHEMBL28750284 | 0.73 | ACHE (0.41) | ELANESMN1; SMN2KMT2AHPGDGSK3B | |
| SCHEMBL9076071 | 0.71 | ELANE (0.36) | ELANEKMT2AATMALDH1A1 | |
| SCHEMBL7079234 | 0.71 | KMT2A (0.40) | ELANEKMT2AATMALDH1A1NPC1 | |
| SCHEMBL29225292 | 0.70 | ELANE (0.38) | ELANEKMT2AATMALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119392-B2 | Biocompatible resists | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2012-02-21 | — | — | US | disclosed |
| US-20050014098-A1 | Biocompatible resists | NORTH CAROLINA AT CHARLOTTE, THE UNIVERSITY OF | 2005-01-20 | — | — | US | disclosed |
| WO-2004099373-A2 | BIOCOMPATIBLE RESISTS | UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2004-11-18 | — | — | WO | disclosed |
| EP-0358524-A2 | Optical material composed of resin having high refractive index | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1990-03-14 | — | — | EP | disclosed |