Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28901969 | 0.81 | PDE4B (0.51) | HPGDMEN1KMT2ACCR5TSHR | |
| SCHEMBL20774839 | 0.79 | MEN1 (0.52) | HPGDLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL28339435 | 0.79 | MEN1 (0.42) | HPGDLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL28487000 | 0.78 | HPGD (0.50) | HPGDLMNAMEN1KMT2AGLA | |
| SCHEMBL31321705 | 0.78 | HPGD (0.58) | HPGDLMNAMEN1KMT2AGLA | |
| SCHEMBL31321722 | 0.77 | HPGD (0.60) | HPGDLMNAKMT2AGLAALDH1A1 | |
| Acetic Acid SCHEMBL10998868 | 0.77 | TSHR (0.53) | HPGDLMNAKMT2AGLATSHR | |
| SCHEMBL28339591 | 0.77 | ALOX15 (0.51) | HPGDLMNAMEN1KMT2ATSHR | |
| SCHEMBL27641736 | 0.76 | KMT2A (0.43) | HPGDMEN1KMT2AMAPK1KDM4E | |
| SCHEMBL182753 | 0.76 | TSHR (0.56) | HPGDLMNAMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621671-A | Benzofuran and benzothiophene derivatives as PGE2 receptor modulators | 爱杜西亚药品有限公司 | 2019-12-27 | — | — | CN | disclosed |
| CN-110612296-A | Phenyl derivatives as PGE2 receptor modulators | 爱杜西亚药品有限公司 | 2019-12-24 | — | — | CN | disclosed |