Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28479252 | 0.94 | ALDH1A1 (0.49) | PDE4BHPGDPOLBALDH1A1MEN1 | |
| SCHEMBL20774839 | 0.83 | MEN1 (0.52) | PDE4BHPGDPOLBALDH1A1MEN1 | |
| SCHEMBL28481675 | 0.83 | PDE4B (0.55) | PDE4BHPGDPOLBALDH1A1MEN1 | |
| SCHEMBL28478306 | 0.83 | CA12 (0.53) | PDE4BHPGDPOLBALDH1A1KMT2A | |
| SCHEMBL28339385 | 0.81 | HPGD (0.55) | HPGDPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL28487133 | 0.80 | PDE4B (0.60) | PDE4BHPGDPOLB | |
| SCHEMBL7364004 | 0.80 | ALDH1A1 (0.46) | HPGDPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL27641736 | 0.79 | KMT2A (0.43) | HPGDPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL28484061 | 0.79 | ALDH1A1 (0.52) | PDE4BHPGDPOLBALDH1A1MEN1 | |
| SCHEMBL28489873 | 0.79 | ALDH1A1 (0.51) | PDE4BHPGDPOLBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111954664-A | Cystic fibrosis transmembrane conductance regulator and methods of use | 艾伯维海外有限公司 | 2020-11-17 | — | — | CN | disclosed |