Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2123778 | 0.80 | TUBB1 (0.40) | THRBLMNASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL31096258 | 0.77 | TUBB1 (0.44) | LMNASMN1; SMN2GAAALDH1A1HSD17B10 | |
| SCHEMBL21823585 | 0.77 | TUBB1 (0.44) | LMNASMN1; SMN2GAAALDH1A1HSD17B10 | |
| SCHEMBL5965055 | 0.76 | ACHE (0.40) | ALOX15LMNASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL28880867 | 0.75 | ALOX15 (0.33) | ALOX15LMNAGAAALDH1A1ESR1 | |
| SCHEMBL418275 | 0.74 | ALOX15 (0.46) | ALOX15LMNASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL1993192 | 0.74 | ALOX15 (0.46) | ALOX15LMNASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL17040889 | 0.73 | TSHR (0.42) | THRBLMNASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL23887370 | 0.73 | PKM (0.55) | ALOX15LMNASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL31316398 | 0.73 | PKM (0.55) | ALOX15LMNASMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621671-A | Benzofuran and benzothiophene derivatives as PGE2 receptor modulators | 爱杜西亚药品有限公司 | 2019-12-27 | — | — | CN | disclosed |