Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 9/20 | 0.61 |
| ▸ | NPC1 | O15118 | 8/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | GPR183 | P32249 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28339610 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNATP53RAB9ANPC1 | |
| SCHEMBL9652216 | 0.91 | RAB9A (0.73) | ALDH1A1LMNATP53RAB9ANPC1 | |
| SCHEMBL9652221 | 0.91 | RAB9A (0.73) | ALDH1A1LMNATP53RAB9ANPC1 | |
| SCHEMBL28342074 | 0.85 | RAB9A (0.61) | ALDH1A1RAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL28339611 | 0.85 | RAB9A (0.83) | ALDH1A1LMNARAB9ANPC1L3MBTL1 | |
| SCHEMBL28339473 | 0.85 | MAPT (0.64) | ALDH1A1LMNARAB9ANPC1L3MBTL1 | |
| SCHEMBL28339474 | 0.85 | MAPT (0.64) | ALDH1A1LMNARAB9ANPC1L3MBTL1 | |
| SCHEMBL28342073 | 0.85 | RAB9A (0.61) | ALDH1A1RAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL28341869 | 0.82 | GPR183 (0.62) | ALDH1A1RAB9ANPC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL28341866 | 0.82 | GPR183 (0.62) | ALDH1A1RAB9ANPC1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483432-A | A kind of acrylic compounds and preparation method thereof, pharmaceutical composition and purposes | UNIV FUDAN | 2019-11-22 | — | — | CN | disclosed |