Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 7/20 | 0.62 |
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28341866 | 1.00 | GPR183 (0.62) | GPR183RAB9ANPC1PKMPTGS2 | |
| SCHEMBL14375112 | 0.92 | RAB9A (0.70) | GPR183RAB9ANPC1PKMPTGS2 | |
| SCHEMBL28339476 | 0.85 | RAB9A (0.65) | RAB9ANPC1ALDH1A1TRPV1L3MBTL1 | |
| SCHEMBL28339475 | 0.85 | RAB9A (0.65) | RAB9ANPC1ALDH1A1TRPV1L3MBTL1 | |
| SCHEMBL30738392 | 0.85 | RAB9A (0.65) | RAB9ANPC1ALDH1A1TRPV1L3MBTL1 | |
| SCHEMBL28339473 | 0.85 | MAPT (0.64) | GPR183RAB9ANPC1ALDH1A1TRPV1 | |
| SCHEMBL28339474 | 0.85 | MAPT (0.64) | GPR183RAB9ANPC1ALDH1A1TRPV1 | |
| SCHEMBL28341788 | 0.84 | RAB9A (0.68) | GPR183RAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL28341787 | 0.84 | RAB9A (0.68) | GPR183RAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL14441226 | 0.83 | PTGS2 (0.62) | GPR183RAB9ANPC1PKMPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483432-A | A kind of acrylic compounds and preparation method thereof, pharmaceutical composition and purposes | UNIV FUDAN | 2019-11-22 | — | — | CN | disclosed |