Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.41 |
| ▸ | CCR8 | P51685 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10829209 | 0.82 | TDP1 (0.46) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL8856826 | 0.81 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL5854396 | 0.81 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL5043710 | 0.81 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL1527657 | 0.81 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL23824720 | 0.81 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL8210825 | 0.81 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL9020889 | 0.81 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL1527655 | 0.81 | TDP1 (0.54) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL6866513 | 0.81 | PTGES (0.45) | TDP1LMNAADRA2ACNR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612119-A | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents | 西雅图儿童医院（DBA西雅图儿童研究所） | 2019-12-24 | — | — | CN | disclosed |