Phthalic Acid

Phthalic Acid

SCHEMBL28339804

C=CCc1c(CC=C)c(C(N)=O)c(CC=C)c(CC=C)c1C(N)=O.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
ALOX15 P16050 1/20 0.47
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 4/20 0.42
HTT P42858 2/20 0.39
AKR1C3 P42330 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 2/20 0.37
HSD17B10 Q99714 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
HMGB1 P09429 1/20 0.37
HPGD P15428 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
NAPRT Q6XQN6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7783028 0.82 KDM4E (0.33) KDM4EHTTTSHRHSD17B10SMN1; SMN2
SCHEMBL176456 0.82 ALDH1A1 (0.35) ALDH1A1KDM4EHTTTSHRMAPT
SCHEMBL9614734 0.81 KDM4E (0.43) ALDH1A1ALOX15KMT2AKDM4EHTT
Phthalic Acid SCHEMBL28549489 0.80 ALDH1A1 (0.61) ALDH1A1ALOX15KMT2AKDM4EHTT
Phthalic Acid SCHEMBL29144166 0.80 ALDH1A1 (0.61) ALDH1A1ALOX15KMT2AKDM4EHTT
SCHEMBL1758773 0.78 ALDH1A1 (0.46) ALDH1A1ALOX15KMT2AKDM4ECYP3A4
SCHEMBL11590643 0.78 MAPT (0.33) ALDH1A1TSHRMAPT
SCHEMBL30331187 0.77 KDM4E (0.32) KDM4EHTTTSHRHSD17B10SMN1; SMN2
Phthalic Acid SCHEMBL7689919 0.77 ALDH1A1 (0.56) ALDH1A1ALOX15KMT2AKDM4EAKR1C3
SCHEMBL28973887 0.77 ALDH1A1 (0.44) ALDH1A1ALOX15KMT2AKDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110494598-A Laminated body and its manufacturing method and gate sealing element NIHON VALQUA KOGYO KK 2019-11-22 CN disclosed