Ethoxycarbonyl Group

Ethoxycarbonyl Group

SCHEMBL28340171

CCOC=O.Cc1cnccc1F

nearest known ligand 0.39

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
LOXL2 Q9Y4K0 1/20 0.33
MMP13 P45452 1/20 0.32
SIRT3 Q9NTG7 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PTGS2 P35354 1/20 0.31
CDC7 O00311 1/20 0.30
DBF4 Q9UBU7 1/20 0.30
KDM4C Q9H3R0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethoxycarbonyl Group SCHEMBL28337925 0.84 LOXL2 (0.36) NAMPTCA12CA1CA2CA9
Ethoxycarbonyl Group SCHEMBL27884606 0.79 CYP11B1 (0.35) NAMPTCA12CA1CA2CA9
SCHEMBL2425486 0.78
Ethoxycarbonyl Group SCHEMBL28254568 0.77 ALDH1A1 (0.38) CA12CA1CA2CA9CA14
Ethoxycarbonyl Group SCHEMBL30844535 0.77 CA12 (0.36) CA12CA1CA2CA9CA14
Ethoxycarbonyl Group SCHEMBL27884564 0.77 CA12 (0.36) CA12CA1CA2CA9CA14
Ethoxycarbonyl Group SCHEMBL29091774 0.77 CYP11B2 (0.35) NAMPTLOXL2
Ethoxycarbonyl Group SCHEMBL30595920 0.77 CYP11B2 (0.35) NAMPTLOXL2
3-Methylpyridine SCHEMBL28078587 0.73 CYP2A6 (0.41) TDP1PTGS2
Amifampridine SCHEMBL28108845 0.73 GAA (0.40) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110590654-A Synthesis method of 4-fluoro-3-substituent-pyridine-2-formate compound 成都睿智化学研究有限公司 2019-12-20 CN disclosed