Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.30 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593042 | 0.81 | LMNA (0.39) | LMNAGLAKDM4EALDH1A1ALOX15 | |
| SCHEMBL28846986 | 0.81 | CYP1A2 (0.39) | LMNANQO1GLAALDH1A1ALOX15 | |
| SCHEMBL28446989 | 0.81 | LMNA (0.39) | LMNANQO1GLAALOX15SMN1; SMN2 | |
| SCHEMBL28523610 | 0.79 | LMNA (0.38) | LMNANQO1GLAALOX15SMN1; SMN2 | |
| SCHEMBL28896473 | 0.78 | LMNA (0.40) | LMNANQO1GLAKDM4EALDH1A1 | |
| SCHEMBL14639041 | 0.78 | NQO1 (0.39) | LMNANQO1KDM4EALDH1A1ALOX15 | |
| SCHEMBL12457978 | 0.77 | NPC1 (0.38) | GLAKDM4EALDH1A1CYP1A2PKM | |
| SCHEMBL28846885 | 0.77 | LMNA (0.40) | LMNANQO1KDM4EALDH1A1MBOAT4 | |
| SCHEMBL17674283 | 0.77 | KDM4E (0.42) | LMNAKDM4EALDH1A1ADRA2AADRA2B | |
| SCHEMBL28549336 | 0.74 | LMNA (0.39) | LMNAGLAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110603252-A | Aryl, heteroaryl and heterocyclic pharmaceutical compounds for the treatment of medical disorders | 艾其林医药公司 | 2019-12-20 | — | — | CN | disclosed |