Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | GRM5 | P41594 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2570298 | 0.86 | KMT2A (0.70) | NPC1RAB9AKMT2AMEN1GRM5 | |
| SCHEMBL7171489 | 0.84 | NPC1 (0.63) | NPC1RAB9AKMT2AMEN1GRM5 | |
| SCHEMBL30798819 | 0.82 | MAOB (0.58) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL23714119 | 0.81 | KDM4E (0.50) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL9755469 | 0.79 | KDR (0.65) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL821839 | 0.77 | KMT2A (1.00) | NPC1RAB9AKMT2AMEN1GRM5 | |
| SCHEMBL6257291 | 0.76 | NPC1 (1.00) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL9753586 | 0.76 | RAB9A (0.88) | NPC1RAB9AKMT2AMEN1GRM5 | |
| SCHEMBL28154257 | 0.73 | MAPT (0.76) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL24733628 | 0.73 | RAB9A (0.63) | NPC1RAB9AKMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108373448-B | Microwave-assisted synthesis method of N- (quinoline-2-yl) aromatic amide | 中南大学 | 2020-01-07 | — | — | CN | disclosed |