Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2570298 | 0.89 | KMT2A (0.70) | KDRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9755467 | 0.89 | L3MBTL1 (0.69) | KDRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL24733628 | 0.87 | RAB9A (0.63) | KDRNPC1RAB9AKMT2AGAA | |
| SCHEMBL9755453 | 0.84 | KMT2A (0.63) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL9755445 | 0.82 | SMN1; SMN2 (0.47) | KDRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL7171489 | 0.81 | NPC1 (0.63) | KDRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL28340968 | 0.79 | NPC1 (0.61) | KDRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL29434873 | 0.79 | KDR (1.00) | KDRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6260903 | 0.79 | KDR (1.00) | KDRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL14775703 | 0.78 | KDR (0.72) | KDRNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005785-A1 | 1,10-PHENANTHROLINE DERIVATIVES | VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDERWIJS (NL) | 1991-05-02 | — | — | WO | disclosed |