Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15550185 | 0.86 | ALOX15 (0.58) | ALOX15ACHELMNAHPGDKDM4E | |
| SCHEMBL27714376 | 0.83 | ALOX15 (0.47) | ALOX15ACHELMNAHPGDKDM4E | |
| SCHEMBL5929563 | 0.83 | ACHE (0.50) | ALOX15ACHELMNAHPGDKDM4E | |
| SCHEMBL28169742 | 0.82 | ALOX15 (0.50) | ALOX15ACHELMNAHPGDKDM4E | |
| SCHEMBL23924761 | 0.81 | FGFR1 (0.53) | ALOX15HPGDKDM4EGLAGAA | |
| SCHEMBL16415282 | 0.81 | KMT2A (0.55) | ALOX15ACHELMNAHPGDKDM4E | |
| SCHEMBL28316306 | 0.81 | ALOX15 (0.50) | ALOX15HPGDKDM4EKMT2AGLA | |
| SCHEMBL5965056 | 0.81 | ALOX15 (0.46) | ALOX15ACHELMNAHPGDKDM4E | |
| SCHEMBL28428387 | 0.81 | ALOX15 (0.49) | ALOX15ACHELMNAHPGDKDM4E | |
| SCHEMBL16397172 | 0.80 | CFD (0.53) | ALOX15HPGDKDM4EGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621671-A | Benzofuran and benzothiophene derivatives as PGE2 receptor modulators | 爱杜西亚药品有限公司 | 2019-12-27 | — | — | CN | disclosed |