Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ITGAL | P20701 | 3/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28341896 | 1.00 | RAB9A (0.56) | RAB9ANPC1KDM4EHPGDHSD11B1 | |
| SCHEMBL28341781 | 0.83 | RAB9A (0.56) | RAB9ANPC1KDM4EHPGDALDH1A1 | |
| SCHEMBL28341779 | 0.83 | RAB9A (0.56) | RAB9ANPC1KDM4EHPGDALDH1A1 | |
| SCHEMBL28341795 | 0.83 | HPGD (0.59) | RAB9ANPC1KDM4EHPGDALDH1A1 | |
| SCHEMBL28339486 | 0.83 | HPGD (0.59) | RAB9ANPC1KDM4EHPGDALDH1A1 | |
| SCHEMBL30738463 | 0.80 | KEAP1 (0.55) | RAB9ANPC1KDM4EHPGDALDH1A1 | |
| SCHEMBL28339655 | 0.80 | KDM4E (0.85) | RAB9ANPC1KDM4EHPGDALDH1A1 | |
| SCHEMBL28339657 | 0.80 | KDM4E (0.85) | RAB9ANPC1KDM4EHPGDALDH1A1 | |
| SCHEMBL28339471 | 0.78 | KDM4E (0.62) | RAB9ANPC1KDM4EHPGDITGAL | |
| SCHEMBL28342073 | 0.77 | RAB9A (0.61) | RAB9ANPC1KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483432-A | A kind of acrylic compounds and preparation method thereof, pharmaceutical composition and purposes | UNIV FUDAN | 2019-11-22 | — | — | CN | disclosed |