Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318862 | 1.00 | KMT2A (0.64) | KMT2ATSHRCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL318460 | 1.00 | KMT2A (0.64) | KMT2ATSHRCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL29841724 | 1.00 | KMT2A (0.64) | KMT2ATSHRCYP1A2CYP2D6CYP3A4 | |
| Hydrochloric Acid SCHEMBL852494 | 0.98 | KMT2A (0.62) | KMT2ATSHRCYP1A2CYP2D6CYP3A4 | |
| Hydrochloric Acid SCHEMBL1143309 | 0.98 | KMT2A (0.62) | KMT2ATSHRCYP1A2CYP2D6CYP3A4 | |
| Hydrochloric Acid SCHEMBL852495 | 0.98 | KMT2A (0.62) | KMT2ATSHRCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL7252180 | 0.89 | KMT2A (0.48) | KMT2ATSHRCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL5514179 | 0.89 | KMT2A (0.52) | KMT2ACYP1A2CYP3A4ALDH1A1PTGS2 | |
| Cadaverine Tartrate SCHEMBL32662849 | 0.88 | KMT2A (0.51) | KMT2ATSHRCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL27865114 | 0.86 | KMT2A (0.53) | KMT2ATSHRCYP1A2CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 456 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101698647-B | Synthesis method of 2,5-diamino benzene ethanol | YIXING XINYU CHEMICAL CO LTD | 2012-10-03 | — | — | CN | claimed |
| CN-101698647-A | Synthesis method of 2,5-diamino benzene ethanol | YIXING XINYU CHEMICAL CO LTD | 2010-04-28 | — | — | CN | claimed |
| US-20070161633-A1 | 4-Bromo-5-(2-chloro-benzoylamino)-1h-pyrazole-3-carboxylic acid (1-aminocarbonyl)eth-1-yl) amide derivatives and related compounds as bradykinin b1 receptor antagonists for the treatment of inflammatory diseases | ELAN PHARMACEUTICALS, INC. (US) | 2007-07-12 | — | — | US | claimed |
| WO-2002020819-A2 | AN ENZYMATIC PROCESS FOR PREPARING β-LACTAM COMPOUNDS | DSM N.V. (NL) | 2002-03-14 | — | — | WO | claimed |
| EP-1186668-A1 | An enzymatic process for preparing Beta-lactam compounds | DSM N.V. (NL) | 2002-03-13 | — | — | EP | claimed |
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | claimed |
| US-12286435-B2 | Compound having benzo seven-membered ring structure, preparation method therefor, and use thereof | BIONNA (BEIJING) MEDICAL TECHNOLOGY CO., LTD. (CN) | 2025-04-29 | — | — | US | disclosed |
| CN-118440082-B | Organic compound, preparation method and application thereof | 天合光能股份有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118480009-A | Compositions and methods for modulating short-chain dehydrogenase activity | 卡斯西部储备大学 | 2024-08-13 | — | — | CN | disclosed |
| CN-118440082-A | Organic compound, preparation method and application thereof | 天合光能股份有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-118390075-A | Synthesis method of glycine ester compound | 中国计量大学 | 2024-07-26 | — | — | CN | disclosed |
| EP-3892272-B1 | BIFUNCTIONAL MOLECULES FOR DEGRADATION OF EGFR AND METHODS OF USE | DANA FARBER CANCER INST INC (US) | 2024-07-24 | — | — | EP | disclosed |
| EP-3919479-B1 | COMPOUND HAVING BENZO SEVEN-MEMBERED RING STRUCTURE, PREPARATION METHOD THEREFOR, AND USE THEREOF | BIONNA BEIJING MEDICAL TECH CO LTD (CN) | 2024-03-20 | — | — | EP | disclosed |
| EP-0404737-A2 | New R(-) 3-quinuclidinol derivatives | BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) | 1990-12-27 | — | — | EP | disclosed |
| EP-0163094-B1 | PREPARATION OF OPTICALLY-ACTIVE ALPHA-SUBSTITUTED PHENYLACETIC ACIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-08-02 | — | — | EP | disclosed |
| US-4661588-A | ANTIBIOTICS | TOYO JOZO KABUSHIKI KAISHA (JP) | 1987-04-28 | — | — | US | disclosed |
| EP-0163094-A2 | Preparation of optically-active alpha-substituted phenylacetic acids | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-12-04 | — | — | EP | disclosed |
| US-4505854-A | Optically active dipeptides and the use thereof as tissue dissolving and histolytic agent in human beings | NATTERMANN & CIE GMBH (DE) | 1985-03-19 | — | — | US | disclosed |
| US-4075405-A | CYANOGEN HALIDE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-02-21 | — | — | US | disclosed |
| US-4001279-A | CARRY INSOLUBLE REAGENT SUBSTANCES INTO SOLUTION IN NON-HYDROXYLIC MEDIA; CROWN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1977-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161633-A1 | 4-Bromo-5-(2-chloro-benzoylamino)-1h-pyrazole-3-carboxylic acid (1-aminocarbonyl)eth-1-yl) amide derivatives and related compounds as bradykinin b1 receptor antagonists for the treatment of inflammatory diseases | BDKRB1, BDKRB2, HRH2 | KMT2A 2943/4885TSHR 1217/4885CYP1A2 689/4885 |
| US-12286435-B2 | Compound having benzo seven-membered ring structure, preparation method therefor, and use thereof | BRD4, BRD7, BICRA | KMT2A 888/4885TSHR 3099/4885CYP1A2 3192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.