SCHEMBL7252180

SCHEMBL7252180

COC(=O)C(N)c1ccc(C(N)C(=O)OC)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 1/20 0.43
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
MT-CO2 P00403 1/20 0.40
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
SLC6A3 Q01959 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CXCR1 P25024 1/20 0.37
CXCR2 P25025 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ACHE P22303 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1143624 0.92 ESR1 (0.54) KMT2AALDH1A1ESR1ESR2MT-CO2
SCHEMBL2585312 0.92 ESR1 (0.54) KMT2AALDH1A1ESR1ESR2MT-CO2
SCHEMBL14032514 0.92 L3MBTL1 (0.46) KMT2AALDH1A1MT-CO2CA12CA1
SCHEMBL8252300 0.92 L3MBTL1 (0.45) KMT2AALDH1A1ESR1ESR2MT-CO2
SCHEMBL8058922 0.92 L3MBTL1 (0.45) KMT2AALDH1A1ESR1ESR2MT-CO2
SCHEMBL1143625 0.92 ESR1 (0.54) KMT2AALDH1A1ESR1ESR2MT-CO2
SCHEMBL9620180 0.92 SLC6A3 (0.47) KMT2AALDH1A1ESR1ESR2MT-CO2
SCHEMBL3504026 0.90 CYP1A2 (0.48) KMT2AALDH1A1SMN1; SMN2CYP1A2MAPK1
SCHEMBL2426957 0.90 RAB9A (0.49) KMT2ACA1CA2SMN1; SMN2CYP1A2
SCHEMBL1969493 0.90 RAB9A (0.49) KMT2ACA1CA2SMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9000219-B2 Method for treatment of isocyanate residue, and method for treatment of carbonate MITSUI CHEMICALS, INC. (JP) 2015-04-07 US disclosed
US-20120271067-A1 METHOD FOR TREATMENT OF ISOCYANATE RESIDUE, AND METHOD FOR TREATMENT OF CARBONATE MITSUI CHEMICALS, INC. 2012-10-25 US disclosed
US-6639101-B2 Catalytic thermal decomposition of carbamates using silicates (clays, zeolites) as catalysts REPSOL QUIMICA, S.A. (ES) 2003-10-28 US disclosed