Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283419 | 1.00 | KMT2A (0.64) | KMT2ATSHRCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL318460 | 1.00 | KMT2A (0.64) | KMT2ATSHRCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL29841724 | 1.00 | KMT2A (0.64) | KMT2ATSHRCYP1A2CYP2D6CYP3A4 | |
| Hydrochloric Acid SCHEMBL852494 | 0.98 | KMT2A (0.62) | KMT2ATSHRCYP1A2CYP2D6CYP3A4 | |
| Hydrochloric Acid SCHEMBL1143309 | 0.98 | KMT2A (0.62) | KMT2ATSHRCYP1A2CYP2D6CYP3A4 | |
| Hydrochloric Acid SCHEMBL852495 | 0.98 | KMT2A (0.62) | KMT2ATSHRCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL7252180 | 0.89 | KMT2A (0.48) | KMT2ATSHRCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL5514179 | 0.89 | KMT2A (0.52) | KMT2ACYP1A2CYP3A4ALDH1A1PTGS2 | |
| Cadaverine Tartrate SCHEMBL32662849 | 0.88 | KMT2A (0.51) | KMT2ATSHRCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL27865114 | 0.86 | KMT2A (0.53) | KMT2ATSHRCYP1A2CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12636386-B2 | Compositions and methods for the treatment and imaging of cancer | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2026-05-26 | — | — | US | disclosed |
| US-20260117216-A1 | MUTANT PENICILLIN ACYLASE AND USES THEREOF | XINGZHI COLLEGE ZHEJIANG NORMAL UNIVERSITY (CN) | 2026-04-30 | — | — | US | disclosed |
| US-12059422-B2 | (Alpha-substituted aralkylamino and heteroarylalkylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, pharmaceutical compositions thereof, and their use in treating proliferative diseases | MEI PHARMA, INC. (US) | 2024-08-13 | — | — | US | disclosed |
| US-20240208959-A1 | THIAZOLE/ISOTHIAZOLE HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM, INC. | 2024-06-27 | — | — | US | disclosed |
| US-20240208959-A1 | THIAZOLE/ISOTHIAZOLE HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM, INC. | 2024-06-27 | — | — | US | disclosed |
| US-20240208959-A1 | THIAZOLE/ISOTHIAZOLE HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM, INC. | 2024-06-27 | — | — | US | disclosed |
| EP-4319872-A1 | THIAZOLE/ISOTHIAZOLE HSD17B13 INHIBITORS AND USES THEREOF | Inipharm, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| US-20230242482-A9 | DISCOVERY, TOTAL SYNTHESIS, AND BIOACTIVITY OF DOSCADENAMIDES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-08-03 | — | — | US | disclosed |
| US-20230159538-A1 | PYRROLIDINE-PYRAZOLES AS PYRUVATE KINASE ACTIVATORS | GLOBAL BLOOD THERAPEUTICS, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230159538-A1 | PYRROLIDINE-PYRAZOLES AS PYRUVATE KINASE ACTIVATORS | GLOBAL BLOOD THERAPEUTICS, INC. | 2023-05-25 | — | — | US | disclosed |
| EP-0983999-A1 | PROCESS FOR PRODUCING AMIDE DERIVATIVES AND INTERMEDIATES | Japan Tobacco Inc. (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0984000-A1 | PROCESS FOR PRODUCING AMIDE DERIVATIVES AND INTERMEDIATE COMPOUNDS | Japan Tobacco Inc. (JP) | 2000-03-08 | — | — | EP | disclosed |
| US-6018066-A | Production of amide derivatives and intermediate compounds therefor | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| US-5962704-A | Production of amide derivatives and intermediate compounds therefor | JAPAN TOBACCO INC. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5777129-A | Hyperbranched polymers | HOECHST CELANESE CORP. (US) | 1998-07-07 | — | — | US | disclosed |
| EP-0846000-A1 | HYPERBRANCHED POLYMERS | HOECHST CELANESE CORPORATION (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5710282-A | Process for preparing substituted aryls | HOECHST CELANESE CORPORATION (US) | 1998-01-20 | — | — | US | disclosed |
| WO-1997006825-A1 | HYPERBRANCHED POLYMERS | HOECHST CELANESE CORPORATION (US) | 1997-02-27 | — | — | WO | disclosed |
| US-5591809-A | Process for preparing hyperbranched polymers | HOECHST CELANESE CORPORATION (US) | 1997-01-07 | — | — | US | disclosed |
| US-5567795-A | Process for preparing hyperbranched polymers | HOECHST CELANESE CORPORATION (US) | 1996-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12059422-B2 | (Alpha-substituted aralkylamino and heteroarylalkylamino) pyrimidinyl and 1,3,5-triazinyl benzimidazoles, pharmaceutical compositions thereof, and their use in treating proliferative diseases | CCNI, CCNK, CCNA1 | KMT2A 2083/4885TSHR 3251/4885CYP1A2 224/4885 |
| US-20260117216-A1 | MUTANT PENICILLIN ACYLASE AND USES THEREOF | ALPL, PEPD, ACSL6 | KMT2A 142/4885TSHR 4555/4885CYP1A2 900/4885 |
| US-20240208959-A1 | THIAZOLE/ISOTHIAZOLE HSD17B13 INHIBITORS AND USES THEREOF | HSD17B1, HSD17B3, HSD17B13 | KMT2A 4050/4885TSHR 1734/4885CYP1A2 58/4885 |
| US-20230242482-A9 | DISCOVERY, TOTAL SYNTHESIS, AND BIOACTIVITY OF DOSCADENAMIDES | PDE9A, CGAS, PDE8A | KMT2A 3296/4885TSHR 1389/4885CYP1A2 2255/4885 |
| US-20230159538-A1 | PYRROLIDINE-PYRAZOLES AS PYRUVATE KINASE ACTIVATORS | PDK1, PDK2, PKM | KMT2A 1420/4885TSHR 2499/4885CYP1A2 3301/4885 |
| US-12636386-B2 | Compositions and methods for the treatment and imaging of cancer | GBA1, GALC, CD47 | KMT2A 872/4885TSHR 887/4885CYP1A2 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.