SCHEMBL28342131

SCHEMBL28342131

Oc1ccccc1C1(Cl)C=CC=CC1O

nearest known ligand 0.30

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
KDM4E B2RXH2 1/20 0.30
NPC1 O15118 1/20 0.30
CA12 O43570 1/20 0.30
GMNN O75496 1/20 0.30
ALDH1A1 P00352 1/20 0.30
EGFR P00533 1/20 0.30
CA2 P00918 1/20 0.30
LMNA P02545 1/20 0.30
FYN P06241 1/20 0.30
POLB P06746 1/20 0.30
CA3 P07451 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
MMP9 P14780 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
NFKB1 P19838 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9788605 0.77 MEN1 (0.34) MEN1KMT2AKDM4ENPC1CA12
SCHEMBL29586709 0.77 MEN1 (0.34) MEN1KMT2AKDM4ENPC1CA12
SCHEMBL4654322 0.77 MEN1 (0.34) MEN1KMT2AKDM4ENPC1CA12
SCHEMBL2030500 0.77
SCHEMBL28672299 0.76 MEN1 (0.30) MEN1KMT2AKDM4ENPC1CA12
SCHEMBL7553960 0.73
SCHEMBL9253524 0.72 THRB (0.36) MEN1KMT2AKDM4ECA12ALDH1A1
SCHEMBL28374793 0.72 CA1 (0.32) CA2
SCHEMBL29148246 0.70 CTSB (0.32) MEN1KMT2AMAPT
SCHEMBL30777406 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110619925-B Method for directly predicting biological effectiveness of organic pollutants 大连理工大学 2022-09-23 CN disclosed
CN-110619925-A Method for directly predicting biological effectiveness of organic pollutants 大连理工大学 2019-12-27 CN disclosed