SCHEMBL29148246

SCHEMBL29148246

O=[N+]([O-])C1(c2ccccc2O)C=CC=CC1O

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CTSB P07858 1/20 0.32
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4654322 0.71 MEN1 (0.34) MEN1MAPTKMT2A
SCHEMBL29586709 0.71 MEN1 (0.34) MEN1MAPTKMT2A
SCHEMBL9788605 0.71 MEN1 (0.34) MEN1MAPTKMT2A
SCHEMBL7621306 0.70 RXRA (0.40)
SCHEMBL28672299 0.70 MEN1 (0.30) MEN1MAPTKMT2A
SCHEMBL28342131 0.70 MEN1 (0.30) MEN1MAPTKMT2A
SCHEMBL9253524 0.70 THRB (0.36) MEN1KMT2A
SCHEMBL7553960 0.68
SCHEMBL8440144 0.67 PLAU (0.35) CTSBMEN1GAAMAPTKMT2A
SCHEMBL28181537 0.67 MEN1 (0.34) MEN1GAAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117486782-A N-substituted carbazole derivative and preparation method and application thereof 中国医学科学院药用植物研究所 2024-02-02 CN disclosed