Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.51 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.51 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.51 |
| ▸ | PIP4K2A | P48426 | 3/20 | 0.42 |
| ▸ | PIP4K2B | P78356 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PIP4K2C | Q8TBX8 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | MAX | P61244 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2834247 | 1.00 | AURKA (0.53) | AURKAMTORPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL2174106 | 0.89 | AURKA (0.66) | AURKAMTORPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL2174102 | 0.89 | AURKA (0.66) | AURKAMTORPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL2877166 | 0.86 | PPARG (0.47) | AURKAMTORPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL2877167 | 0.86 | PPARG (0.47) | AURKAMTORPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL1672813 | 0.79 | PRKAG1 (0.84) | AURKAMTORPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL1672814 | 0.79 | PRKAG1 (0.84) | AURKAMTORPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL2172044 | 0.76 | AURKA (0.75) | AURKAMTORPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL2172045 | 0.76 | AURKA (0.75) | AURKAMTORPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL2172223 | 0.75 | AURKA (0.71) | AURKAMTORPRKAG1PRKAA1PRKAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254576-A1 | ANDROGEN RECEPTOT-ABLATIVE AGENTS | The Ohio State University Research Foundation (US) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009105621-A1 | ANDROGEN RECEPTOT-ABLATIVE AGENTS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2009-08-27 | — | — | WO | disclosed |