Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.63 |
| ▸ | MAOB | P27338 | 3/20 | 0.63 |
| ▸ | CA12 | O43570 | 2/20 | 0.63 |
| ▸ | CA1 | P00915 | 2/20 | 0.63 |
| ▸ | CA2 | P00918 | 2/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.63 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.63 |
| ▸ | CA9 | Q16790 | 2/20 | 0.63 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.63 |
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.63 |
| ▸ | MAOA | P21397 | 2/20 | 0.63 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.63 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.63 |
| ▸ | XDH | P47989 | 1/20 | 0.63 |
| ▸ | LCK | P06239 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143392 | 0.93 | CYP19A1 (0.68) | CYP19A1MAOBCA12CA1CA2 | |
| Flavone SCHEMBL27682451 | 0.84 | TNKS (0.84) | CYP19A1MAOBCA12CA1CA2 | |
| Flavone SCHEMBL6301585 | 0.84 | TNKS (0.84) | CYP19A1MAOBCA12CA1CA2 | |
| SCHEMBL22197372 | 0.84 | LCK (0.77) | CYP19A1MAOBCA12CA1CA2 | |
| Flavone SCHEMBL29279409 | 0.82 | TNKS (0.81) | CYP19A1MAOBCA12CA1CA2 | |
| Flavone SCHEMBL28343013 | 0.81 | TNKS (0.79) | CYP19A1MAOBCA12CA1CA2 | |
| Flavone SCHEMBL28343014 | 0.81 | TNKS (0.79) | CYP19A1MAOBCA12CA1CA2 | |
| 6-Aminoflavone SCHEMBL31550004 | 0.81 | EGFR (0.82) | CYP19A1CA12CA1CA2ABCB1 | |
| 6-Aminoflavone SCHEMBL926716 | 0.81 | EGFR (0.82) | CYP19A1CA12CA1CA2ABCB1 | |
| SCHEMBL17786600 | 0.78 | EGFR (0.82) | CYP19A1CA12CA1CA2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107163096-B | Troxerutin amide derivative and synthesis method and application thereof | 河南工业大学 | 2020-01-14 | — | — | CN | disclosed |