Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 5/20 | 0.77 |
| ▸ | EGFR | P00533 | 2/20 | 0.76 |
| ▸ | SRC | P12931 | 1/20 | 0.76 |
| ▸ | MAOB | P27338 | 6/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | MPO | P05164 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | QPCT | Q16769 | 1/20 | 0.61 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.61 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.57 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.57 |
| ▸ | PRKDC | P78527 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143392 | 0.90 | CYP19A1 (0.68) | LCKEGFRSRCMAOBCYP19A1 | |
| SCHEMBL31364277 | 0.87 | MAOB (0.81) | LCKMAOBCYP19A1CYP3A4HPGD | |
| SCHEMBL29711102 | 0.85 | PLA2G2A (0.81) | LCKEGFRSRCMAOBCYP19A1 | |
| Phosphoric Acid SCHEMBL28343041 | 0.84 | CYP19A1 (0.63) | LCKEGFRSRCMAOBCYP19A1 | |
| SCHEMBL10885932 | 0.82 | TNKS (0.71) | LCKEGFRSRCMAOBCYP19A1 | |
| SCHEMBL925553 | 0.78 | EGFR (0.82) | LCKEGFRSRCMAOBCYP3A4 | |
| SCHEMBL17786600 | 0.78 | EGFR (0.82) | LCKEGFRSRCCYP19A1CYP3A4 | |
| SCHEMBL29374176 | 0.78 | LCK (1.00) | LCKEGFRSRCMAOBCYP19A1 | |
| SCHEMBL3644507 | 0.78 | LCK (1.00) | LCKEGFRSRCMAOBCYP19A1 | |
| SCHEMBL4993162 | 0.78 | EGFR (0.77) | LCKEGFRSRCCYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3677262-A1 | KAEMPFEROL ANALOG-CONTAINING COMPOSITION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2020-07-08 | — | — | EP | disclosed |