Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8134521 | 0.81 | ALDH1A1 (0.50) | ALOX5AOC3LMNAKDM4EALDH1A1 | |
| SCHEMBL28345940 | 0.80 | AOC3 (0.56) | AOC3TAAR1POLB | |
| SCHEMBL28345908 | 0.79 | SMN1; SMN2 (0.44) | LMNATAAR1ALDH1A1NPC1RAB9A | |
| SCHEMBL28343167 | 0.79 | CYP1A2 (0.43) | KDM4ETAAR1ALDH1A1FFAR1SLC5A1 | |
| SCHEMBL498481 | 0.79 | F2RL1 (0.59) | F2RL1ALOX5LMNAKDM4ECALM1 | |
| SCHEMBL8566732 | 0.79 | ALOX5 (0.66) | F2RL1ALOX5AOC3ALDH1A1POLB | |
| SCHEMBL11197690 | 0.78 | F2RL1 (0.58) | F2RL1AOC3LMNAKDM4ECALM1 | |
| SCHEMBL11270504 | 0.77 | F2RL1 (0.53) | F2RL1ALOX5LMNAKDM4ECALM1 | |
| SCHEMBL28345992 | 0.77 | ALDH1A1 (0.50) | ALOX5AOC3TAAR1ALDH1A1FFAR1 | |
| SCHEMBL6581242 | 0.76 | NPC1 (0.59) | F2RL1KDM4EALDH1A1FFAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590627-B | Synthesis method of 3-aryl thiopropionamide derivative | 温州大学 | 2022-01-14 | — | — | CN | disclosed |
| CN-110590627-A | Synthesis method of 3-aryl thiopropionamide derivative | 温州大学 | 2019-12-20 | — | — | CN | disclosed |