Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.66 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.54 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.51 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31329297 | 0.90 | ALOX5 (0.82) | ALOX5F2RL1ALDH1A1POLBKMT2A | |
| SCHEMBL3988521 | 0.86 | ALOX5 (0.62) | ALOX5F2RL1ALDH1A1FFAR1POLB | |
| SCHEMBL25767343 | 0.86 | ALOX5 (0.62) | ALOX5F2RL1ALDH1A1FFAR1POLB | |
| SCHEMBL755827 | 0.81 | HTT (0.59) | ALOX5ALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL7329940 | 0.81 | F2RL1 (0.85) | ALOX5F2RL1ALDH1A1FFAR1POLB | |
| SCHEMBL17230518 | 0.80 | ALOX5 (0.59) | ALOX5F2RL1ALDH1A1FFAR1POLB | |
| SCHEMBL22504109 | 0.80 | FFAR1 (0.46) | ALOX5FFAR1POLB | |
| SCHEMBL7442885 | 0.80 | KMT2A (0.77) | ALOX5F2RL1ALDH1A1POLBNPC1 | |
| SCHEMBL31169772 | 0.80 | KMT2A (0.55) | ALOX5F2RL1ALDH1A1FFAR1POLB | |
| SCHEMBL17230519 | 0.80 | ALOX5 (0.55) | ALOX5F2RL1ALDH1A1FFAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |
| CN-119331033-A | Catalyst CudppfBH4And its use in catalyzing the reduction of alpha, beta-unsaturated amides | 安徽大学 | 2025-01-21 | — | — | CN | disclosed |
| WO-2008024337-A2 | COMPOUNDS AND METHODS FOR INHIBITING THE INTERACTION OF BCL PROTEINS WITH BINDING PARTNERS | INFINITY DISCOVERY, INC. (US) | 2008-02-28 | — | — | WO | disclosed |