Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28345919 | 0.81 | TAAR1 (0.50) | TAAR1MEN1KMT2ADAO | |
| SCHEMBL4435822 | 0.80 | TAAR1 (0.57) | TAAR1SIGMAR1SLC6A3RIPK1ADRA2C | |
| SCHEMBL28346001 | 0.80 | TAAR1 (0.57) | TAAR1CTSLCTSBSIGMAR1 | |
| SCHEMBL28343161 | 0.80 | TAAR1 (0.57) | TAAR1SIGMAR1RIPK1FFAR1MEN1 | |
| SCHEMBL28345992 | 0.78 | ALDH1A1 (0.50) | TAAR1CTSLFFAR1KMT2A | |
| SCHEMBL28345940 | 0.78 | AOC3 (0.56) | TAAR1SIGMAR1 | |
| SCHEMBL7955428 | 0.77 | TAAR1 (0.57) | TAAR1SLC6A3FFAR1DAO | |
| SCHEMBL27383068 | 0.74 | TAAR1 (0.53) | TAAR1SLC6A3FFAR1DAO | |
| SCHEMBL2290 | 0.74 | ALDH1A1 (0.60) | TAAR1SLC6A3FFAR1DAO | |
| SCHEMBL28499656 | 0.73 | SIGMAR1 (0.54) | SIGMAR1HTR2BFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590627-B | Synthesis method of 3-aryl thiopropionamide derivative | 温州大学 | 2022-01-14 | — | — | CN | disclosed |
| CN-110590627-A | Synthesis method of 3-aryl thiopropionamide derivative | 温州大学 | 2019-12-20 | — | — | CN | disclosed |