Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2290 | 0.85 | ALDH1A1 (0.60) | TAAR1SLC6A3FFAR1DAOMAOB | |
| SCHEMBL3371633 | 0.80 | TAAR1 (0.74) | TAAR1SLC6A3IDO1AGXTDAO | |
| SCHEMBL7340106 | 0.80 | TAAR1 (0.57) | TAAR1SLC6A3FFAR1DAOCASP3 | |
| SCHEMBL3025521 | 0.79 | TAAR1 (0.50) | TAAR1IDO1AGXTMAOB | |
| SCHEMBL334758 | 0.78 | FFAR1 (0.68) | TAAR1FFAR1CASP3CASP7 | |
| SCHEMBL23901663 | 0.78 | IAPP (0.56) | TAAR1FFAR1DAOMAOBCASP3 | |
| SCHEMBL22537825 | 0.78 | TAAR1 (0.50) | TAAR1SLC6A3IDO1AGXTDAO | |
| SCHEMBL10110719 | 0.78 | TAAR1 (0.50) | TAAR1SLC6A3FFAR1DAODRD2 | |
| SCHEMBL1447034 | 0.77 | TAAR1 (0.53) | TAAR1SLC6A3FFAR1DAOCASP3 | |
| SCHEMBL2857831 | 0.77 | TAAR1 (0.58) | TAAR1IDO1AGXTFFAR1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274602-B1 | ADMINISTERING COMPOSTITIONS SUCH AS 3,3-DIMETHYL-1-((2S)-2-(5-(3-PYRIDYL) PENTANOYL)-1-PYRROLIDINE)-1, 2-PENTANEDIONE TO TREAT ALOPECIA OR PROMOTING HAIR GROWTH IN ANIMALS | GPI NIL HOLDINGS, INC. | 2001-08-14 | — | — | US | disclosed |