Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 3/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL247590 | 0.88 | CES2 (0.59) | ALOX15TSHRCES2CES1L3MBTL1 | |
| SCHEMBL28775846 | 0.88 | CES2 (0.59) | ALOX15TSHRCES2CES1L3MBTL1 | |
| SCHEMBL27863223 | 0.88 | LMNA (0.48) | TSHRCES2CES1L3MBTL1SRD5A2 | |
| SCHEMBL247591 | 0.84 | CES2 (0.65) | ALOX15TSHRCES2CES1L3MBTL1 | |
| SCHEMBL28343283 | 0.84 | CES2 (0.54) | ALOX15TSHRCES2CES1L3MBTL1 | |
| SCHEMBL18050295 | 0.82 | CES2 (0.52) | ALOX15TSHRCES2CES1L3MBTL1 | |
| SCHEMBL18050293 | 0.82 | CES2 (0.52) | ALOX15TSHRCES2CES1L3MBTL1 | |
| SCHEMBL21879688 | 0.81 | TSHR (0.60) | ALOX15TSHRCES2CES1SRD5A2 | |
| SCHEMBL19921939 | 0.81 | PDCD1 (0.48) | L3MBTL1NPC1RAB9ASMN1; SMN2CA1 | |
| Biphenyl SCHEMBL3127994 | 0.81 | CES2 (0.55) | ALOX15TSHRCES2CES1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621678-A | Antitumor compounds | 法马马有限公司 | 2019-12-27 | — | — | CN | disclosed |