Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28187499 | 1.00 | GPR84 (0.48) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL27602895 | 0.98 | GPR84 (0.45) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL7207181 | 0.92 | CA2 (0.43) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL31302713 | 0.90 | PPARG (0.50) | FFAR1MAPTPPARDFFAR4FAAH | |
| SCHEMBL31302726 | 0.90 | PPARG (0.50) | FFAR1MAPTPPARDFFAR4FAAH | |
| SCHEMBL31112441 | 0.84 | GPR84 (0.44) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL28876599 | 0.84 | FAAH (0.47) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL5694212 | 0.84 | FAAH (0.47) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL31112442 | 0.84 | GPR84 (0.44) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL21811922 | 0.84 | FAAH (0.47) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110709393-A | Inhibitors of LDHA activity | 阿克蒂克制药股份有限公司 | 2020-01-17 | — | — | CN | disclosed |