SCHEMBL28344110

SCHEMBL28344110

N=C(N)c1ccc(-c2ccc(C(=N)N)cn2)nc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HA1 P13674 1/20 0.52
P4HTM Q9NXG6 1/20 0.52
UBE2T Q9NPD8 2/20 0.52
LMNA P02545 2/20 0.46
PLAU P00749 2/20 0.46
MASP2 O00187 1/20 0.46
THPO P40225 1/20 0.46
PRSS1 P07477 5/20 0.44
F2 P00734 3/20 0.44
PRSS3 P35030 2/20 0.44
APEX1 P27695 1/20 0.44
ST14 Q9Y5Y6 1/20 0.43
PRMT5 O14744 1/20 0.43
PRMT1 Q99873 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
CYP2C19 P33261 1/20 0.43
HSD17B10 Q99714 1/20 0.43
F10 P00742 2/20 0.42
F12 P00748 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8975475 0.86 WDR5 (0.53) UBE2TLMNAPLAUMASP2THPO
SCHEMBL3788282 0.86 NQO2 (0.49) P4HA1P4HTMUBE2TLMNAPLAU
SCHEMBL14433310 0.84 NQO2 (0.53) P4HA1P4HTMUBE2TPLAUF2
SCHEMBL8975609 0.84 RXFP1 (0.49) P4HA1P4HTMUBE2TLMNAPLAU
SCHEMBL14507287 0.84 NQO2 (0.47) P4HA1P4HTMUBE2TLMNAPLAU
Hydrochloric Acid SCHEMBL3788110 0.84 NQO2 (0.47) P4HA1P4HTMUBE2TLMNAPRSS1
SCHEMBL3505298 0.82 NQO2 (0.52) UBE2TPLAUPRSS1F2ST14
SCHEMBL20428452 0.81 KDM1A (0.46) UBE2TF10F7WDR5
SCHEMBL14433307 0.78 NQO2 (0.63) UBE2TPRMT1ALDH1A1HPGDHSD17B10
SCHEMBL20554192 0.77 UBE2T (0.49) UBE2TLMNAPLAUMASP2THPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115094463-B Sub-nano alloy material and preparation method and application thereof 中国科学院上海高等研究院 2023-10-13 CN claimed
CN-115094463-A Sub-nanometer alloy material and preparation method and application thereof 中国科学院上海高等研究院 2022-09-23 CN claimed
CN-110628038-B Covalent triazine organic framework, limited-area metal catalyst, preparation method and application 中国科学院上海高等研究院 2022-03-29 CN claimed
CN-110628038-A Covalent triazine organic framework, limited-area metal catalyst, preparation method and application 中国科学院上海高等研究院 2019-12-31 CN claimed
CN-115094463-B Sub-nano alloy material and preparation method and application thereof 中国科学院上海高等研究院 2023-10-13 CN disclosed
CN-115094463-A Sub-nanometer alloy material and preparation method and application thereof 中国科学院上海高等研究院 2022-09-23 CN disclosed
CN-110628038-B Covalent triazine organic framework, limited-area metal catalyst, preparation method and application 中国科学院上海高等研究院 2022-03-29 CN disclosed
CN-110628038-A Covalent triazine organic framework, limited-area metal catalyst, preparation method and application 中国科学院上海高等研究院 2019-12-31 CN disclosed