Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 2/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | F9 | P00740 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | F11 | P03951 | 2/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | UBE2T | Q9NPD8 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975475 | 0.87 | WDR5 (0.53) | NQO2UBE2TRXFP1NPC1LDHA | |
| SCHEMBL8975609 | 0.86 | RXFP1 (0.49) | NQO2UBE2TRXFP1NPC1LDHA | |
| SCHEMBL12647420 | 0.83 | HPGDS (0.55) | KDM1ARXFP1NPC1LDHABAZ2B | |
| SCHEMBL14369783 | 0.81 | WDR5 (0.47) | NQO2UBE2TRXFP1NPC1LDHA | |
| SCHEMBL28344110 | 0.81 | P4HA1 (0.52) | F10F7UBE2TWDR5 | |
| SCHEMBL8975727 | 0.80 | RXFP1 (0.44) | NQO2RXFP1NPC1LDHABAZ2B | |
| SCHEMBL27702582 | 0.79 | NPC1 (0.67) | KDM1ARXFP1NPC1LDHACCR1 | |
| SCHEMBL27439089 | 0.78 | HPGDS (0.43) | NQO2UBE2TRXFP1NPC1LDHA | |
| SCHEMBL2013410 | 0.77 | WDR5 (0.54) | NQO2WDR5 | |
| SCHEMBL16991665 | 0.77 | NPC1 (0.51) | KDM1ARXFP1NPC1LDHABAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-B1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS AS DGAT-1 INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-08-01 | — | — | EP | disclosed |