Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 3/20 | 0.63 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3788282 | 0.92 | NQO2 (0.49) | NQO2UBE2T | |
| Hydrochloric Acid SCHEMBL3788110 | 0.90 | NQO2 (0.47) | NQO2UBE2T | |
| SCHEMBL14507287 | 0.90 | NQO2 (0.47) | NQO2UBE2T | |
| SCHEMBL5307850 | 0.84 | NQO2 (0.85) | NQO2WDR5PRMT1ALDH1A1TOP1 | |
| SCHEMBL3505979 | 0.82 | NQO2 (0.81) | NQO2WDR5PRMT1ALDH1A1TOP1 | |
| SCHEMBL8975475 | 0.81 | WDR5 (0.53) | NQO2WDR5PRMT1ALDH1A1UBE2T | |
| SCHEMBL8975609 | 0.80 | RXFP1 (0.49) | NQO2WDR5PRMT1ALDH1A1UBE2T | |
| SCHEMBL28344110 | 0.78 | P4HA1 (0.52) | WDR5PRMT1ALDH1A1UBE2THPGD | |
| SCHEMBL14433311 | 0.78 | NQO2 (0.41) | NQO2ALDH1A1KDM4EGAAAPP | |
| SCHEMBL5487186 | 0.78 | NQO2 (0.41) | NQO2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256203-B2 | Dicationic 2,5-diarylfuran aza-analogs as anti-protozoan agents | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2007-08-14 | — | — | US | disclosed |
| US-7256203-B2 | Dicationic 2,5-diarylfuran aza-analogs as anti-protozoan agents | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2007-08-14 | — | — | US | disclosed |