Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.56 |
| ▸ | ELANE | P08246 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28344334 | 0.95 | SHMT2 (0.56) | SHMT2ELANETP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL4121482 | 0.85 | POLB (0.56) | ELANESMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL28345153 | 0.81 | KDM4E (0.55) | ELANESMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL28880876 | 0.80 | KMT2A (0.53) | ELANETP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL16505799 | 0.79 | HPGD (0.53) | SHMT2ELANETP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL28341789 | 0.79 | ELANE (0.48) | ELANETP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL753481 | 0.78 | POLB (0.51) | SHMT2ELANETP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL28827584 | 0.77 | SHMT2 (0.46) | SHMT2ELANETP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL30033509 | 0.77 | SHMT2 (0.46) | SHMT2ELANETP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL29634332 | 0.77 | ELANE (0.53) | SHMT2ELANETP53SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627721-B | Phenanthridine compound and synthesis method thereof | 陕西科技大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-110627721-A | Phenanthridine compound and synthesis method thereof | 陕西科技大学 | 2019-12-31 | — | — | CN | disclosed |