Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28345153 | 0.88 | KDM4E (0.55) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL4121482 | 0.87 | POLB (0.56) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL28341789 | 0.86 | ELANE (0.48) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL28344334 | 0.85 | SHMT2 (0.56) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL28341918 | 0.84 | KDM4E (0.45) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL28383910 | 0.83 | KDM4E (0.68) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL28344367 | 0.80 | SHMT2 (0.56) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL8394469 | 0.80 | NPC1 (0.57) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL10484070 | 0.79 | KMT2A (0.59) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL29634332 | 0.79 | ELANE (0.53) | KMT2AMEN1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627721-B | Phenanthridine compound and synthesis method thereof | 陕西科技大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-110627721-A | Phenanthridine compound and synthesis method thereof | 陕西科技大学 | 2019-12-31 | — | — | CN | disclosed |