SCHEMBL4121482

SCHEMBL4121482

CCOC(=O)c1nc2ccccc2c2ccccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.56
SMN1; SMN2 Q16637 5/20 0.55
KMT2A Q03164 4/20 0.55
MEN1 O00255 3/20 0.55
LMNA P02545 1/20 0.55
KDM4E B2RXH2 6/20 0.54
GLA P06280 1/20 0.54
ALDH1A1 P00352 2/20 0.53
MAPK1 P28482 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
MAPT P10636 3/20 0.51
ELANE P08246 2/20 0.51
GAA P10253 2/20 0.51
NPSR1 Q6W5P4 2/20 0.51
NPY1R P25929 1/20 0.51
NPY2R P49146 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
GPR55 Q9Y2T6 1/20 0.51
SCN9A Q15858 1/20 0.50
CYP1A2 P05177 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28345153 0.89 KDM4E (0.55) POLBSMN1; SMN2KMT2AMEN1LMNA
SCHEMBL28880876 0.87 KMT2A (0.53) POLBSMN1; SMN2KMT2AMEN1LMNA
SCHEMBL28341789 0.86 ELANE (0.48) POLBSMN1; SMN2KMT2AMEN1LMNA
SCHEMBL28344367 0.85 SHMT2 (0.56) SMN1; SMN2KMT2AMEN1LMNAKDM4E
SCHEMBL28344334 0.85 SHMT2 (0.56) SMN1; SMN2KMT2AMEN1LMNAKDM4E
SCHEMBL28341918 0.84 KDM4E (0.45) POLBSMN1; SMN2KMT2AMEN1LMNA
SCHEMBL6822555 0.83 KDM4E (0.53) POLBSMN1; SMN2KMT2AMEN1LMNA
SCHEMBL10756337 0.83 MAPT (0.61) POLBSMN1; SMN2KMT2AMEN1LMNA
SCHEMBL28977964 0.83 SMN1; SMN2 (0.51) POLBSMN1; SMN2KMT2AMEN1LMNA
SCHEMBL16504846 0.83 KDM4E (0.53) POLBSMN1; SMN2KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110627721-B Phenanthridine compound and synthesis method thereof 陕西科技大学 2022-06-14 CN disclosed
CN-110627721-A Phenanthridine compound and synthesis method thereof 陕西科技大学 2019-12-31 CN disclosed
US-8258302-B2 Method for producing benzazepinone API CORPORATION (JP) 2012-09-04 US disclosed
US-20090171090-A1 METHOD FOR PRODUCING BENZAZEPINONE API CORPORATION (JP) 2009-07-02 US disclosed
EP-1985615-A1 METHOD FOR PRODUCING BENZAZEPINONE API Corporation (JP) 2008-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090171090-A1 METHOD FOR PRODUCING BENZAZEPINONE NISCH, GABBR1, GABBR2 POLB 2316/4885SMN1; SMN2 3973/4885KMT2A 1792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.