1,3-Propanediol

1,3-Propanediol

SCHEMBL28344604

O=C(O)c1ccco1.OCCCO

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.54
CES1 P23141 1/20 0.54
PTPN1 P18031 1/20 0.53
ALDH1A1 P00352 5/20 0.50
ERCC5 P28715 1/20 0.50
FEN1 P39748 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.49
PKM P14618 1/20 0.49
POLB P06746 3/20 0.47
RECQL P46063 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
THRB P10828 1/20 0.47
APEX1 P27695 1/20 0.47
RAB9A P51151 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
NPC1 O15118 2/20 0.46
HPGD P15428 3/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL28026131 0.92 CES2 (0.58) CES2CES1PTPN1ALDH1A1ERCC5
Hydrocinnamyl Alcohol SCHEMBL27945830 0.89 SMN1; SMN2 (0.53) CES2CES1PTPN1ALDH1A1ERCC5
SCHEMBL24446 0.87
SCHEMBL3811314 0.87 CES2 (0.68) CES2CES1PTPN1ALDH1A1ERCC5
Octacosanol SCHEMBL5935751 0.86 GAA (0.50) CES2CES1PTPN1ALDH1A1ERCC5
Alcohol SCHEMBL28296602 0.86 CES2 (0.56) CES2CES1PTPN1ALDH1A1ERCC5
SCHEMBL25196785 0.85
SCHEMBL9580893 0.85 CES2 (0.65) CES2CES1PTPN1ALDH1A1ERCC5
Ammonia Solution, Strong SCHEMBL6719610 0.85
Hydrochloric Acid SCHEMBL753936 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107206673-B Soluble material for three-dimensional modeling 花王株式会社 2020-01-14 CN disclosed