Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,3-Propanediol SCHEMBL28344604 | 0.86 | CES2 (0.54) | HDAC3POLBRAB9AALDH1A1PKM | |
| SCHEMBL28495892 | 0.84 | GAA (0.48) | GAAHDAC3POLBRAB9ADNMT1 | |
| Alcohol SCHEMBL28296602 | 0.84 | CES2 (0.56) | GAAHDAC3POLBRAB9AALDH1A1 | |
| SCHEMBL27459701 | 0.84 | HDAC3 (0.50) | GAAHDAC3POLBRAB9ADNMT1 | |
| Ethylene Glycol SCHEMBL28026131 | 0.82 | CES2 (0.58) | POLBRAB9AALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL28882576 | 0.81 | ALDH1A1 (0.59) | POLBRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL28493498 | 0.81 | HDAC3 (0.50) | GAAHDAC3POLBRAB9AALDH1A1 | |
| Hydrocinnamyl Alcohol SCHEMBL27945830 | 0.80 | SMN1; SMN2 (0.53) | HDAC3RAB9AALDH1A1SMN1; SMN2KMT2A | |
| Butyl Alcohol SCHEMBL27800138 | 0.79 | HDAC3 (0.51) | GAAHDAC3POLBALDH1A1PKM | |
| SCHEMBL4418222 | 0.79 | PTGS1 (0.58) | GAARAB9AALDH1A1PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060020135-A1 | Long chain aliphatic alcohol derivatives and methods of making and using same | SINO PHARMACEUTICALS CORPORATION (CA) | 2006-01-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060020135-A1 | Long chain aliphatic alcohol derivatives and methods of making and using same | ADH1C, ADH5, NAPRT | GAA 2647/4885HDAC3 251/4885POLB 2363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.