Hydrochloric Acid

Hydrochloric Acid

SCHEMBL753936

Cl.O=C(O)c1ccco1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29276658 0.98 CES2 (0.62)
SCHEMBL3811314 0.97 CES2 (0.68)
SCHEMBL24446 0.97
SCHEMBL3467845 0.95
Ammonia Solution, Strong SCHEMBL6719610 0.95
SCHEMBL25212901 0.95
Ammonia Solution, Strong SCHEMBL30994934 0.95 CES2 (0.65)
SCHEMBL25196785 0.95
Water SCHEMBL728285 0.95
SCHEMBL9580893 0.95 CES2 (0.65)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118878524-A Near infrared fluorescent probe for detecting carboxylesterase and having antibacterial activity, and preparation method and application thereof 许昌学院 2024-11-01 CN claimed
EP-0146642-B1 PROCESS FOR THE PREPARATION OF 4-AMINO-6,7-DIMETHOXY-2-(4-(FUROYL-2)-PIPERAZIN-1-YL)-QUINAZOLINE AND ITS PHYSIOLOGICALLY ACCEPTABLE SALT LUDWIG HEUMANN &amp; CO GMBH (DE) 1988-01-20 EP claimed
US-4088668-A Acetylene derivatives MERRELL TORAUDE ET COMPAGNIE (FR) 1978-05-09 US claimed
CN-119529236-A Epoxy resin composition, epoxy resin composition containing reinforcing fibers, prepreg, thermoplastic resin, and fiber-reinforced plastic 日铁化学材料株式会社 2025-02-28 CN disclosed
CN-118878524-A Near infrared fluorescent probe for detecting carboxylesterase and having antibacterial activity, and preparation method and application thereof 许昌学院 2024-11-01 CN disclosed
CN-118724866-A Oxime ester photoinitiator, photo-curing resin composition and application 常州强力先端电子材料有限公司 2024-10-01 CN disclosed
EP-2154186-B1 CROSSLINKABLE POLYVINYL ACETAL POROUS POWDER, METHOD FOR PRODUCING THE SAME, AND USE OF THE SAME KURARAY CO (JP) 2019-09-18 EP disclosed
CN-108200760-A BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS 英安塔制药有限公司 2018-06-22 CN disclosed
EP-2266958-B1 Antiviral agent SHIONOGI & CO (JP) 2017-03-15 EP disclosed
US-20170066754-A1 ANTIVIRAL AGENT SHIONOGI & CO., LTD. (JP) 2017-03-09 US disclosed
CN-104822678-B Compound with muscarinic receptor antagonist and beta 2-adrenergic receptor agonists activity 奇斯药制品公司 2017-03-08 CN disclosed
US-4029808-A Thienyl phenyl O-(aminoalkyl)-ketone oxime and furyl phenyl O-(aminoalkyl)-ketone oxime coronary vasodilators C.E.R.P.H.A. A FRENCH SOCIETY ORGANISED UNDER THE LAWS OF FRANCE (FR) 1977-06-14 US disclosed
US-4018814-A ANTHELMINTICS BAYER AKTIENGESELLSCHAFT (DT) 1977-04-19 US disclosed
US-4013676-A NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DT) 1977-03-22 US disclosed
US-4010164-A ANALGESIC, MORPHINE ANTAGONIST BOEHRINGER INGELHEIM GMBH (DT) 1977-03-01 US disclosed
US-3998960-A ANALGESIC, ANTITUSSIVE, OPIATE ANTAGONIST BOEHRINGER INGELHEIM GMBH (DT) 1976-12-21 US disclosed
US-3996247-A ANTHELMINTIC BAYER AKTIENGESELLSCHAFT (DT) 1976-12-07 US disclosed
US-3969529-A Phenoxyacetic acid derivatives as diuretic agents C.E.R.P.H.A. (FR) 1976-07-13 US disclosed
US-3966938-A Treatment of thrombosis and the inhibition of blood platelet aggregation SANDOZ LTD. (CH) 1976-06-29 US disclosed
US-3931194-A ANALGESIC, ANTITUSSIVE, OPIATE ANTAGONIST BOEHRINGER INGELHEIM GMBH (DT) 1976-01-06 US disclosed