Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21839795 | 0.82 | AR (0.40) | ARPGR | |
| SCHEMBL1914296 | 0.78 | GABRA1 (0.36) | ARPGR | |
| SCHEMBL10088537 | 0.78 | AR (0.45) | AR | |
| SCHEMBL30444423 | 0.76 | AR (0.44) | ARPGR | |
| SCHEMBL1762439 | 0.76 | GAA (0.47) | ARPGR | |
| SCHEMBL20535166 | 0.76 | AR (0.44) | ARPGR | |
| SCHEMBL3347622 | 0.72 | FFAR1 (0.40) | AR | |
| SCHEMBL17672783 | 0.71 | NOTUM (0.52) | AR | |
| SCHEMBL1530568 | 0.69 | CYP17A1 (0.48) | AR | |
| SCHEMBL20455567 | 0.68 | PTGES (0.36) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678450-B | Isoxazole derivatives as nuclear receptor agonists and uses thereof | 日东制药株式会社 | 2023-06-20 | — | — | CN | disclosed |
| CN-110678450-A | Isoxazole derivatives as nuclear receptor agonists and uses thereof | 日东制药株式会社 | 2020-01-10 | — | — | CN | disclosed |