Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 6/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | UBE2M | P61081 | 2/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20475113 | 0.90 | HSD11B1 (0.38) | CHRM1CHRM3CHRM2HTR2AOPRM1 | |
| SCHEMBL29929920 | 0.82 | P2RX3 (0.40) | CHRM1CHRM3CHRM2HTR2AUBE2M | |
| SCHEMBL2820222 | 0.80 | HSD11B1 (0.45) | AGTR2 | |
| SCHEMBL20475134 | 0.77 | HDAC8 (0.44) | OPRM1ALDH1A1SMN1; SMN2MMP1MMP2 | |
| SCHEMBL26966069 | 0.75 | HSD11B1 (0.52) | AGTR2 | |
| SCHEMBL28345071 | 0.75 | MEN1 (0.39) | UBE2MDCUN1D1ALDH1A1MMP1MMP2 | |
| SCHEMBL13841900 | 0.74 | HSD11B1 (0.43) | AGTR2 | |
| SCHEMBL2817569 | 0.74 | HSD11B1 (0.43) | AGTR2 | |
| SCHEMBL20475202 | 0.73 | HSD11B1 (0.36) | CHRM1CHRM3CHRM2HTR2AOPRM1 | |
| SCHEMBL29666567 | 0.71 | HCRTR2 (0.49) | CHRM1CHRM3CHRM2HTR2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110546136-A | proline-based neuropeptide FF receptor modulators | RES TRIANGLE INST | 2019-12-06 | — | — | CN | disclosed |