Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27725014 | 0.90 | TSHR (0.55) | CA12CA2CA7CA9CA14 | |
| SCHEMBL6881151 | 0.87 | TSHR (0.56) | CA12CA2CA7CA9CA14 | |
| SCHEMBL31647133 | 0.85 | CA12 (0.50) | CA12CA2CA7CA9CA14 | |
| SCHEMBL8431843 | 0.84 | CA12 (0.66) | CA12CA2CA7CA9CA14 | |
| Hydrochloric Acid SCHEMBL6289084 | 0.83 | CA12 (0.64) | CA12CA2CA7CA9CA14 | |
| SCHEMBL17057851 | 0.81 | ALDH1A1 (0.58) | CA12CA2CA7CA9CA14 | |
| SCHEMBL4621966 | 0.81 | BACE1 (0.42) | CA12CA2CA7CA9CA14 | |
| SCHEMBL11784914 | 0.80 | LMNA (0.56) | CA12CA2CA7CA9CA14 | |
| SCHEMBL18677456 | 0.80 | TSHR (0.55) | CA12CA2CA7CA9CA14 | |
| SCHEMBL20267768 | 0.80 | GABRP (0.46) | TSHRALDH1A1GABRA1GABRB2LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107096036-B | Preparation method and application of pH-sensitive hyaluronic acid-doxorubicin nano prodrug | 武汉理工大学 | 2020-01-14 | — | — | CN | disclosed |