SCHEMBL2834550

SCHEMBL2834550

CCOc1ccc2c(ccc3sncc32)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.46
MAPT P10636 3/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP11B1 P15538 2/20 0.43
CYP11B2 P19099 2/20 0.43
CYP19A1 P11511 1/20 0.43
TRPM5 Q9NZQ8 1/20 0.42
KMT2A Q03164 6/20 0.41
TP53 P04637 2/20 0.41
CYP3A4 P08684 2/20 0.41
TSHR P16473 1/20 0.41
MEN1 O00255 4/20 0.38
LMNA P02545 2/20 0.38
THRB P10828 2/20 0.38
TERT O14746 1/20 0.38
ABCB11 O95342 1/20 0.38
BLM P54132 1/20 0.38
ABL1 P00519 1/20 0.38
AKR1C3 P42330 1/20 0.38
AKR1C2 P52895 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL926949 0.83 PDE3B (0.45) MAPTALDH1A1CYP11B1CYP11B2CYP19A1
SCHEMBL18417197 0.80 NQO1 (0.56) HSD17B10MAPTALDH1A1CYP11B1CYP11B2
SCHEMBL8965547 0.80 KMT2A (0.50) HSD17B10MAPTALDH1A1CYP11B1CYP11B2
SCHEMBL12259987 0.79 NQO1 (0.54) HSD17B10MAPTALDH1A1CYP11B1CYP11B2
SCHEMBL12269044 0.77 NQO1 (0.52) HSD17B10MAPTALDH1A1CYP11B1CYP11B2
SCHEMBL8471534 0.73 ALDH1A1 (0.46) HSD17B10MAPTALDH1A1CYP11B1CYP11B2
SCHEMBL29629327 0.73 NQO1 (0.68) HSD17B10MAPTALDH1A1CYP11B1CYP11B2
SCHEMBL3825385 0.73 NQO1 (0.68) HSD17B10MAPTALDH1A1CYP11B1CYP11B2
SCHEMBL12227908 0.73 MAPK1 (0.50) HSD17B10MAPTALDH1A1CYP11B1CYP11B2
SCHEMBL928218 0.72 NPC1 (0.43) HSD17B10MAPTALDH1A1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859954-B2 Planographic printing plate precursor and stack thereof FUJIFILM CORP (JP) 2017-11-08 EP disclosed
EP-1901124-B1 Image recording material FUJIFILM CORP (JP) 2010-06-30 EP disclosed
US-7741005-B2 A planographic printing plate precursor comprising: an aluminum support; and a photosensitive layer including a polymerization initiator, a polymerizable compound and a binder polymer; an oxygen barrier layer; and a protective layer including a filler; capable of image formation FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
EP-1839853-B1 Planographic printing plate precursor and stack thereof FUJIFILM CORP (JP) 2009-07-08 EP disclosed
EP-1859954-B1 Planographic printing plate precursor and stack thereof FUJIFILM CORP (JP) 2008-11-12 EP disclosed
US-7445882-B2 Image recording material FUJIFILM CORPORTATION (JP) 2008-11-04 US disclosed
EP-1901124-A1 Image recording material FUJIFILM Corporation (JP) 2008-03-19 EP disclosed
US-20080057439-A1 Image recording material FUJIFILM CORPORATION (JP) 2008-03-06 US disclosed
EP-1859954-A1 Planographic printing plate precursor and stack thereof FUJIFILM Corporation (JP) 2007-11-28 EP disclosed
US-20070231740-A1 A planographic printing plate precursor comprising: an aluminum support; and a photosensitive layer including a polymerization initiator, a polymerizable compound and a binder polymer; an oxygen barrier layer; and a protective layer including a filler; capable of image formation FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
EP-1839853-A1 Planographic printing plate precursor and stack thereof FUJIFILM Corporation (JP) 2007-10-03 EP disclosed