Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA6 | P23280 | 2/20 | 0.45 |
| ▸ | CA5A | P35218 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL911369 | 0.80 | CYP1A2 (0.46) | KMT2AALDH1A1HSD17B10CYP3A4TSHR | |
| SCHEMBL2834550 | 0.80 | HSD17B10 (0.46) | KMT2AALDH1A1HSD17B10TP53CYP3A4 | |
| SCHEMBL8966123 | 0.79 | CA12 (0.49) | KMT2ACA12CA1CA7CA9 | |
| SCHEMBL12059762 | 0.78 | SLC6A2 (0.46) | TRPM5TRPA1 | |
| SCHEMBL12338017 | 0.76 | APP (0.40) | CA12CA1CA4CA6CA7 | |
| SCHEMBL3825385 | 0.74 | NQO1 (0.68) | KMT2AALDH1A1HSD17B10TP53CYP3A4 | |
| SCHEMBL29629327 | 0.74 | NQO1 (0.68) | KMT2AALDH1A1HSD17B10TP53CYP3A4 | |
| SCHEMBL827195 | 0.71 | MAPT (0.50) | KMT2AALDH1A1HSD17B10TP53CYP3A4 | |
| SCHEMBL23458226 | 0.71 | NQO1 (0.62) | KMT2AALDH1A1HSD17B10TP53CYP3A4 | |
| SCHEMBL3821099 | 0.71 | NQO1 (0.62) | KMT2AALDH1A1HSD17B10TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530136-B1 | Nematicidal agents | CIBA GEIGY AG (CH) | 1996-02-21 | — | — | EP | claimed |
| US-5451595-A | Benzoisothiazole ethers | CIBA-GEIGY CORPORATION (US) | 1995-09-19 | — | — | US | claimed |
| EP-0530136-A2 | Nematicidal agents | CIBA-GEIGY AG (CH) | 1993-03-03 | — | — | EP | claimed |
| EP-0530136-B1 | Nematicidal agents | CIBA GEIGY AG (CH) | 1996-02-21 | — | — | EP | disclosed |
| US-5451595-A | Benzoisothiazole ethers | CIBA-GEIGY CORPORATION (US) | 1995-09-19 | — | — | US | disclosed |
| EP-0530136-A2 | Nematicidal agents | CIBA-GEIGY AG (CH) | 1993-03-03 | — | — | EP | disclosed |