Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | TGM1 | P22735 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20522606 | 0.87 | PTGER4 (0.43) | FFAR1LMNAKDM4EGABRA1GABRG2 | |
| SCHEMBL30719897 | 0.80 | FFAR1 (0.39) | MAPTFFAR1LMNAL3MBTL1KDM4E | |
| SCHEMBL30719900 | 0.80 | FFAR1 (0.39) | MAPTFFAR1LMNAL3MBTL1KDM4E | |
| SCHEMBL31305594 | 0.80 | FFAR1 (0.39) | MAPTFFAR1LMNAL3MBTL1KDM4E | |
| SCHEMBL22712757 | 0.74 | GABRP (0.42) | MAPTFFAR1KDM4EGABRA1GABRG2 | |
| SCHEMBL3688513 | 0.74 | CA12 (0.55) | FFAR1RAB9ALMNAKDM4ENR1H4 | |
| SCHEMBL3688515 | 0.74 | CA12 (0.55) | FFAR1RAB9ALMNAKDM4ENR1H4 | |
| SCHEMBL5989565 | 0.73 | LMNA (0.45) | MAPTFFAR1RAB9ALMNAAKR1B10 | |
| SCHEMBL5989569 | 0.73 | LMNA (0.45) | MAPTFFAR1RAB9ALMNAAKR1B10 | |
| SCHEMBL5691251 | 0.73 | MAPT (0.63) | MAPTRAB9ALMNAL3MBTL1F13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678458-A | Substituted cyclyl-acetic acid derivatives for the treatment of metabolic disorders | 武田药品工业株式会社 | 2020-01-10 | — | — | CN | disclosed |